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TIXiMED, Inc. is focused on developing and commercializing TXNIP inhibiting medication as a first-of-its-kind oral therapeutic for Type 1 and Type 2 diabetes. TIXiMED is the exclusive license holder for the patent (composition of matter and method of use) surrounding TIX100, a novel small molecule that normalizes pancreatic beta cell TXNIP, a detrimental protein elevated in Type 1 and Type 2 diabetes. Increased TXNIP causes pancreatic islet dysfunction and death of insulin-producing beta cells and thereby contributes to the development and progression of diabetes. Diabetes affects more than half a billion people worldwide. Those affected by Type 1 diabetes are dependent on multiple daily insulin injections or continuous insulin infusions to stay alive and manage their blood sugar. Oral anti-diabetic drugs are only approved for Type 2 diabetes, but can be associated with multiple side effects, underlining the need for novel and better oral diabetes medications for Type 1 and Type 2 diabetes. TXNIP inhibition has recently been demonstrated to be an effective and safe therapeutic approach in adults and children with recent onset Type 1 diabetes and TIX100 shows beneficial, anti-diabetic effects in 4 different mouse models. Advantages of TIX100 include oral availability, no associated hypoglycemia or weight gain, potent inhibition of detrimental TXNIP in human islets, and a favorable pharmacokinetic and safety profile. In addition, TIX100 inhibits excessive glucagon secretion and hepatic glucose production and protects against fatty liver. Thus, TIX100 holds promise for durable, weight-neutral improvement in glycemic control in Type 1 and Type 2 diabetes by targeting common underlying pathology and promoting patients own islet cell health.
Kodezi is an AI platform providing tools to maximise efficiency when programming. Our initial product consists of an auto-correct for programmers, which serves as a Grammarly for programming languages.
kovitz systems inc is a Brooklyn, NY-based company in the Business Services sector.
avad3, Inc. has been providing professional video and audio for events since 2011. We are a flexible, growing team of professionals that leverage our young age balanced with production experience to bring a fresh perspective to our industry. We are here because we love to serve.
At AllaiHealth, we are revolutionizing healthcare by providing cutting edge digital solutions, powered by AI/ML, that empower healthcare professionals, care teams and patients to better manage chronic health conditions. Built by doctors for doctors, we reduce administrative burdens throughout the care journey, and facilitate better patient provider communication. Our platform serves as a valuable service for customers, enabling time savings through efficient pre-visit planning, and personalized care plans. We are committed to delivering the right information at the right time, contributing to improved health outcomes and cost savings. AllaiHealth aims to be the leading provider of AI-driven personalized care journeys. We integrate with EMRs and utilize intelligent questionnaires to aggregate data that provides a holistic view of every patient. By doing so, we enable better and more efficient communication between patients and providers, reduce the burden of finding past and present health information, and ultimately lead to improved outcomes. Our goal is to empower physicians to focus on patient care, reduce administrative tasks, and provide timely, accurate, and actionable insights during the encounter and beyond, thereby improving patient outcomes and enhancing the overall healthcare experience. AllaiHealth is creating consumer-grade experiences at the point of care and beyond by building the tools physicians and care teams require to engage in a meaningful shared decision making process for personalized care planning.