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Surface Oncology is a clinical-stage immuno-oncology company focused on using its specialized knowledge of the biological pathways critical to the immunosuppressive tumor microenvironment (TME) for the development of next-generation therapies to help patients suffering with cancer. Recent advances in understanding how the immune system fights cancer has created a first wave of immunotherapies with profound benefits for some patients. These first-generation therapies, or "checkpoint inhibitors", have been groundbreaking, but only a relatively small subset of patients is deriving long-term benefit. We believe that the lack of a broad and sustained clinical response is because these first-generation therapies only target one component of the immunosuppressive TME and a broader, more multi-faceted therapeutic approach is required. We are a team on a mission to deliver transformative outcomes for people with cancer by breaking through the frontiers of immuno-oncology research. Our diverse clinical and preclinical pipeline of immune-enhancing antibody candidates target the innate and adaptive arms of the immune system to deliver dramatically different therapies for patients and their families. Surface is leveraging its deep understanding of TME biology to target factors and cells that suppress patients’ anti-tumor immune response. Our broad attack on the TME has the potential to convert patients’ non-responsive ‘cold’ tumors into immune-active ones. We push ourselves to break through across all dimensions of our work. From a discovery perspective, Surface leverages its world-class SAB to identify new targets and takes an aggressive approach towards generating diverse, highly-specific antibodies, which allows our scientists to thoroughly explore the relevant biology. Our antibody discovery approach generates therapeutic-quality antibodies, as well as unique tools to explore the biology of the tumor microenvironment.
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Dungarvin is a national organization of privately owned companies that are dedicated to providing high quality, community-based supports to people with varying support needs. Founded in St. Paul, Minnesota in 1976, Dungarvin has grown to employ approximately 3,500 people who currently provide supports to over 3,200 individuals across 13 states. We believe all persons faced with the challenges of a disability have the same rights and the same basic needs as do other citizens without disabilities. Dungarvin`s mission and values apply to every person we serve, including those with significant behavioral, medical and physical challenges. We are committed to principles of self-determination, self-actualization, and to the preservation of dignity of each person we serve, regardless of the nature or degree of their needs. Dungarvin`s mission is respecting and responding to the choices of people in need of supports. Dungarvin provides a variety of individually tailored services and supports including supported living, day services, supported employment, case management, supported foster care, children`s services, respite care, elder care, host homes and supports for persons with traumatic brain injury and mental health needs in several states.
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