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Eloxx Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company developing novel RNA-modulating drug candidates that are designed to treat rare and ultra-rare premature stop codon diseases. Premature stop codons are point mutations that disrupt protein synthesis from messenger RNA. As a consequence, patients with premature stop codon diseases have reduced or eliminated protein production from the mutation bearing allele accounting for some of the most severe phenotypes in these genetic diseases. These premature stop codons have been identified in over 1,800 rare and ultra-rare diseases. Read-through therapeutic development is focused on extending mRNA half-life and increasing protein synthesis by enabling the cytoplasmic ribosome to read through premature stop codons to produce full-length proteins. Eloxx`s lead product candidate, ELX-02, is a small molecule drug candidate designed to restore production of full-length functional proteins. ELX-02 is in the early stages of clinical development focusing on cystic fibrosis and cystinosis. ELX-02 is an investigational drug that has not been approved by any global regulatory body. Eloxx is headquartered in Waltham, MA, with R&D operations in Rehovot, Israel.
Pharmacyclics, an AbbVie company, is a biopharmaceutical company located in Sunnyvale, CA employing more than 900 people. We focus on developing and commercializing innovative small-molecule therapies for the treatment of certain cancers and immune-mediated diseases.
Enclara Pharmacia is the combination resulting from the August 2014 acquisition of Hospice Pharmacia by Enclara Health. We believe that this marriage creates the only true solution for hospice mail order pharmacy services and augments an already robust PBM local offering for hospices that want a choice in their pharmacy service model. Andy Horowitz, CEO, continues to lead Enclara Pharmacia. Enclara Pharmacia serves over 500 hospice providers and 84,000 hospice patients per day nationwide. Enclara’s mail order model provides comprehensive pharmacy support, delivering medications directly to hospice patients’ homes, with the backup of local pharmacies to serve their same-day and emergency needs. Comprehensive services include pharmacist consultation 24/7, patient Drug Utilization Review (DUR), Conditions of Participation (CoP) reports, formulary management, account management, and online reporting—all bundled into a predictable per diem reimbursement model. Enclara Pharmacia’s PBM Plus offering provides you with abundant choice and access to our powerful local pharmacy network contracting platform. The service is offered at a fee for service (FFS) price, unbundled, allowing you to choose the level of clinical intervention, if any, your hospice requires, and to “pay as you go” as those resources are utilized. The program gives the control back to you, supporting overall cost containment.
Hepalink was established in 1998 and restructured in 2007 to be a limited liability company.
Javelin Pharmaceuticals is a Cambridge, MA-based company in the Healthcare, Pharmaceuticals, and Biotech sector.