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Center for Functional Genomics is a Rensselaer, NY-based company in the Healthcare, Pharmaceuticals, and Biotech sector.
Libra Therapeutics is focused on developing novel disease-modifying therapeutics that can restore the cellular balance disrupted in neurodegenerative diseases.
Zynerba (NASDAQ: ZYNE) is dedicated to improving the lives of people with rare and near rare neuropsychiatric disorders where there is a high unmet medical need by pioneering the development and commercialization of next-generation pharmaceutically-produced cannabinoid therapeutics formulated for transdermal delivery. Cannabinoids interact with specific receptors throughout the body to produce pharmacologic effects, primarily in the CNS and immune systems. Transdermal delivery has the potential to reduce adverse effects associated with oral dosing because it allows the drug to be absorbed through the skin directly into the bloodstream, avoiding the gastrointestinal tract and lessening the opportunity for GI-related adverse events. It also avoids first-pass liver metabolism, potentially enabling lower dosage levels of active pharmaceutical ingredients with a higher bioavailability and an improved safety profile. Zynerba`s lead patent-protected product candidate in clinical development is ZYN002: ZYN002 is the first and only pharmaceutically-produced cannabidiol (CBD) formulated as a permeation-enhanced gel for transdermal delivery. Through a proprietary combination of our pharmaceutically-produced CBD and permeation enhancers, we believe we can effectively deliver CBD through the layers of the epidermis and into the circulatory system. The company is currently assessing ZYN002 in Fragile X syndrome and certain adult and pediatric refractory epilepsies. These include adult refractory focal epilepsy and developmental and epileptic encephalopathies (DEE), a heterogeneous group of rare and ultra-rare epilepsy syndromes associated with severe cognitive impairment and behavioral disturbances.
Canadian Light Source is a Saskatoon, SK-based company in the Healthcare, Pharmaceuticals, and Biotech sector.
Chromatin is unlocking the potential of plants to produce greater value and meaningful products for consumers, growers, seed producers, and processors. At the same time, the company's technology can benefit the environment through decreased use of pesticides and fertilizers. The company's mini-chromosome technology simultaneously introduces multiple genetic traits into plants, reducing the time and cost required to develop improved and novel crop-based products, such as medicines, biomaterials, textiles and nutritionally improved foods. These products are enabled while allowing growers to enjoy the benefits of the most up-to-date agronomic traits, such as herbicide tolerance, pest resistance, and diseases resistance. Mini-chromosomes also provide unprecedented precision and control of new traits at every point in a plant's life cycle, from seed to field and beyond. Crop stewardship is at the core of Chromatin's values, and the company is equally focused on using its technology to introduce sustainable, healthy agricultural practices while enhancing commercial value and quality of life.