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KaloBios is a biopharmaceutical company dedicated to helping the lives of patients with innovative therapies. Our mission is to improve the lives of cancer patients with innovative, Humaneered®, monoclonal antibodies. KaloBios` Humaneered® antibodies are next generation, customized antibodies designed to overcome challenges limiting today`s marketed antibody products. Using our expertise, our antibodies are customized to enhance a desired effect or reduce a possible undesired effect. Our pipeline is comprised of Humaneered® antibodies. These antibodies are being investigated in clinical development programs focused on treating cancer: KB004 (anti-EphA3) Humaneered® mAb to treat patients with hematologic malignancies, solid tumors, and their stem cells; currently enrolling patients with myelofibrosis and myelodysplastic syndrome in the company’s Phase 2 expansion portion of its Phase 1/2 clinical trial in hematologic malignancies; and KB003 (anti-GM-CSF) Humaneered® mAb that KaloBios intends to evaluate in oncology indications where GM-CSF may play a key role in such indications as chronic myelomonocytic leukemia (CMML). KaloBios intends to commence clinical evaluation of KB003 in this patient population beginning in the second half of 2015. We use a patient-targeted approach utilizing or developing a screen or diagnostic method to identify those patients most likely to benefit from our treatments.
RS Design is a Hawthorne, NJ-based company in the Healthcare, Pharmaceuticals, and Biotech sector.
BrunMed is a Sackville, NB-based company in the Healthcare, Pharmaceuticals, and Biotech sector.
Ripple is a Salt Lake City, UT-based company in the Healthcare, Pharmaceuticals, and Biotech sector.
Relievant Medsystems, Inc., a privately held medical device company pioneering the INTRACEPT therapy of nerve ablation within vertebral bodies for the treatment of chronic low back pain (CLBP). The INTRACEPT Intraosseous Nerve Ablation System is a patent-protected, minimally invasive, implant-free therapy that utilizes radiofrequency energy delivered into the vertebral body of the spine to ablate the Basivertebral Nerve (BVN). This nerve, characterized in peer-reviewed literature reporting studies of pain signal transmission and in preclinical and clinical evaluations, is a significant contributor in the transduction of pain arising from degeneration of the vertebral bodies associated with CLBP. The INTRACEPT Intraosseous Nerve Ablation System leverages proprietary instruments and methods to disable this nerve.